TSRL is a preclinical CRO focused on helping pharmaceutical, biotech, and academic teams progress early drug candidates with confidence. Our scientists work directly with your team to reduce risk, generate high-quality data, and create alignment with development goals.

We offer integrated support across formulation, bioanalysis, PK and ADME, toxicology, drug delivery technologies, and early strategy planning. Every service is guided by scientific clarity and customized to meet your timeline and therapeutic needs.

Based in Ann Arbor, Michigan, TSRL’s 7,200 sq. ft. facility has 5,000 sq. ft. of wet lab space, including analytical chemistry, formulation, in vitro, and in vivo testing. 

 

Core Preclinical Services

 

Formulation Development

Bioanalysis

Tailored approaches to improve solubility, enhance stability, and meet delivery requirements

High-sensitivity drug quantification using HPLC and LC-MS/MS for pharmacokinetic, safety, and toxicology studies

 

Strategic Consulting

PK, ADME, and Toxicology

Planning and guidance to close knowledge gaps, align with regulatory needs, and support clear decision-making

Studies designed to assess how compounds are absorbed, distributed, metabolized, and eliminated, along with early insights into toxicology

 
 
 

Drug Delivery Technology

 

Support for novel delivery systems including MAP technology to help address challenges with compliance, convenience, and compound stability

 

Hundreds of Sponsors Turn to TSRL to Help Develop Better Medicines for Underserved Populations

 
 

How We Support Progress

TSRL combines scientific insight with practical experience to help move your program forward. Our work is guided by collaboration, transparency, and a strong track record in early development.

  • Study designs tailored to the molecule and project goals

  • Cross-functional coordination across formulation, bioanalysis, and PK

  • Scientific staff with decades of development experience

  • Clear documentation, quality control, and regular updates at every stage

 
 

TSRL in the News

Ready to Discuss Your Program?

Connect with a TSRL scientist to understand how our preclinical CRO services can support your team and your next milestone.